AAKG - 120 kaps.

What's with the arginine?

Arginine is currently enjoying great interest. It is classified as a conditionally essential amino acid - the amount that is synthesized in the body is often insufficient, hence it must be supplied from the outside. It participates in various anabolic and catabolic transformations taking place in the human body. According to the available scientific knowledge (Campbell et al., 2006), arginine is of great importance in the synthesis of cytoplasmic and nuclear proteins, other amino acids, creatine and the urea cycle.

Urea is synthesized from arginine to allow the body to remove excess ammonia, which is bad for cells. L-arginine is also classified as a glucogenic amino acid because it can be metabolized to alpha-ketoglutarate (AKG) and enter the citric acid cycle. However, one of the most important roles played by L-arginine is participation in the synthesis of nitric oxide (NO). Studies clearly show that exogenously administered L-arginine promotes biological effects mediated by nitric oxide.

Important nitric oxide, or a few words about the phenomenon known as the muscle pump

It is well known that L-arginine is a precursor in the biosynthesis of nitric oxide, which acts as a messenger to trigger vasodilation and increase blood flow. Nitric oxide production from L-arginine occurs in many different cell types, including skeletal muscle. The authors of another scientific publication on L-arginine supplementation (Wax et al., 2012) report that it is believed that the increase in nitric oxide allows for improved blood flow, which may be beneficial for people performing resistance exercise. In addition, increasing blood flow could theoretically improve exercise capacity by increasing nutrient delivery and/or waste removal from exercising skeletal muscles.

AAKG, or L-arginine alpha-ketoglutarate

Wax et al. also report in their publication that L-arginine is combined with alpha-ketoglutarate to further improve exercise capacity by increasing ATP production. Alpha-ketoglutarate is a metabolite that is formed in the process of the Krebs cycle. External administration of alpha-ketoglutarate in the form of a supplement, e.g. as L-arginine alpha-ketoglutarate (AAKG), may increase the flow of the Krebs cycle and affect the saving of glutamate in the body. And glutamate is an essential amino acid, among others. for protein anabolism.

AAKG in capsules

If your training plan includes intense physical effort, then L-arginine in the form of L-arginine alpha-ketoglutarate may be the perfect solution for you! Be sure to try AAKG in a convenient form of capsules.

Bibliography:

1. Wax B., Kavazis A. N., Webb H. E., Brown S. P., Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men, Journal of the International Society of Sports Nutrition, 2012, 9, 17.
2. Campbell B., Roberts M., Kerksick C., Wilborn C., Marcello B. (et al.), Pharmacokinetics, safety, and effects on exercise performance of alpha-arginine-ketoglutarate in trained adult men, Nutrition 22 (2006), 872-881.
3. Bogdański P., Pupek-Musialik D., Jabłecka A., Bryl W., Suplementacja L-argininy w nadciśnieniu tętniczym - fakty i kontrowersje, Nadciśnienie Tętnicze, 2001, tom 5, nr 2, s. 133-139.