FLEX PAK - 400g | Collagen

Do you feel that you are heavily exploiting your bones and joints?

Do you train intensively and your physical activity is focused only on specific goals? Or maybe you are just looking for a comprehensive product whose individual ingredients are important for the musculoskeletal system? If so, we have the perfect offer for you! In our offer you will find a product that is the answer to the needs of most of us. Remember that the osteoarticular system is the support and protection of our body. This is always worth bearing in mind. FLEX PAK is a complex formula whose active ingredients perfectly match each other.

How important is collagen?

Collagen (especially type I and II) are the most important structural and functional components of the extracellular matrix of tendons, ligaments and cartilage. Quantitative and qualitative changes in the structure of the matrix (e.g. reduced collagen content) are detected by tissue-specific cells, which stimulates anabolic and catabolic processes in order to regulate the physiological composition of extracellular matrix macromolecules[1].

What is collagen hydrolyzate?

Hydrolyzed collagen is a form of collagen also called collagen hydrolyzate. Collagen hydrolysates are extensively processed to break down large collagen molecules into smaller fragments for increased absorption. To produce hydrolyzed collagen, collagen is denatured and then hydrolyzed, resulting in very low molecular weight collagen peptides. These lower molecular weight collagen peptides may be more easily absorbed in the small intestine, theoretically making them more likely to be delivered to other areas of the body, including the joints[2].

Proline and vitamin C are important for collagen

The most common amino acids in collagen are glycine and proline or its derivative, hydroxyproline. Proline and hydroxyproline together account for about 23% of the amino acid content in the collagen molecule. Of the body's stores of hydroxyproline, approximately 99.8% is found in collagen, making tests for this amino acid useful as a marker of total collagen. Both proline and hydroxyproline are essential for the biosynthesis, structure and strength of collagen[3]. As for vitamin C, it also plays a role in collagen synthesis. Vitamin C helps in the proper production of collagen to ensure the proper functioning of bones, cartilage, skin, but also blood vessels, gums and teeth[4].

Glucosamine, chondroitin and MSM and their importance

Glucosamine is a water-soluble monosaccharide amino acid and one of the most abundant monosaccharides in the human body. It is present in large amounts in the articular cartilage, being a component of glycosaminoglycans in the cartilage matrix, as well as in the synovial fluid. Chondroitin sulphate is also classified as glycosaminoglycans and is also the main component of the extracellular matrix of joint cartilage. It plays a major role in creating a significant osmotic pressure that expands the matrix and causes tension of the collagen network. It provides cartilage with strength and flexibility to withstand tensile stresses under various loading conditions[5]. MSM, or methylsulfonylmethane, is an organic form of sulfur that plays an important role in many organs and body systems. It takes part in various physiological processes, including i.a. in the synthesis of collagen and hyaluronic acid[6].

The addition of calcium, magnesium and vitamin B6

Calcium is needed to maintain healthy bones and teeth and helps in the proper functioning of muscles. In turn, vitamin B6 contributes to the maintenance of proper protein and glycogen metabolism and to the reduction of tiredness and fatigue[4].

Now you know why FLEX PAK is a perfectly matched active ingredient. Simply JOINTS & BONES SUPPORT!

Bibliography:

1. Zdzieblik D., Brame J., Oesser S., Gollhofer A., König D., The Influence of Specific Bioactive Collagen Peptides on Knee Joint Discomfort in Young Physically Active Adults: A Randomized Controlled Trial. Nutrients, 2021, Feb 5;13(2):523.
2. Mobasheri A., Mahmoudian A., Kalvaityte U., Uzieliene I., Larder C. E., Iskandar M. M., Kubow S., Hamdan P. C., de Almeida C. S. Jr, Favazzo L. J., van Loon L. J. C., Emans P. J., Plapler P. G., Zuscik M. J., A White Paper on Collagen Hydrolyzates and Ultrahydrolyzates: Potential Supplements to Support Joint Health in Osteoarthritis? Current Rheumatolgy Reports, 2021, Oct 30;23(11):78.
3. Albaugh V. L., Mukherjee K., Barbul A., Proline Precursors and Collagen Synthesis: Biochemical Challenges of Nutrient Supplementation and Wound Healing. The Journal of Nutrition, 2017, Nov;147(11):2011-2017.
4. Rozporządzenie Komisji (UE) NR 432/2012 z dnia 16 maja 2012 r. ustanawiające wykaz dopuszczonych oświadczeń zdrowotnych dotyczących żywności, innych niż oświadczenia odnoszące się do zmniejszenia ryzyka choroby oraz rozwoju i zdrowia dzieci.
5. Vasiliadis H. S., Tsikopoulos K., Glucosamine and chondroitin for the treatment of osteoarthritis. World Journal of Orthopedics, 2017, Jan 18;8(1):1-11.
6. Muizzuddin N., Benjamin R., Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves signs of skin ageing. International Journal vor Vitamin and Nutrition Research, 2020, Feb 21:1-10.